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About

Nathan TeuscherI have been teaching and training for over 11 years in the pharmaceutical industry. I developed on-line training tools for Pharmacy students, provided general pharmacokinetics lectures for non-PK scientists, given specialized training in population pharmacokinetics, and developed intuitive software tools to aid in pharmacokinetic analysis. My dynamic teaching style helps students understand the material and integrate the concepts into practice.

Education

2002

PhD

Pharmaceutical Sciences

University of Michigan

1999

MS

Pharmaceutical Sciences

University of Michigan

1997

BS

Biochemistry

Brigham Young University

Professional Organizations

  • American Association of Pharmaceutical Scientists (AAPS)

  • International Society of Neurochemistry (ISN)

  • American Society of Clinical Pharmacology and Therapuetics (ASCPT)

  • American College of Clinical Pharmacology (ACCP)

Experience

  • Senior Director, Clinical Pharmacology, Reata Pharmaceuticals (July 2011 – Present)

  • Acting Director, Clinical Pharmacology, Alcon Research Ltd. (May 2009 – July 2011)

  • Founder and President, PK/PD Associates (Sep 2008 – Present)

  • Director, Clinical Pharmacology, MDS Pharma Services (Dec 2006 – Present)

  • Associate Director, PK/PD, MDS Pharma Services (Nov 2005 – Dec 2006)

  • Clinical Pharmacokineticist, NPS Pharmaceuticals (Jul 2003 - Nov 2005)

  • Drug Metabolism Scientist, NPS Pharmaceuticals (Jun 2002 - Jul 2003)

  • Graduate Teaching Assistant, University of Michigan (Sep 2001 - May 2002)

Awards

  • Lincoln Business Journal’s Top 40 Under 40, 2008 

  • Walter F. Enz Award for Excellence in Pharmaceutics, 2001

  • AAPS PPDM/CS Graduate Symposium, 2001

  • Distinguished Faculty and Graduate Student Seminar, 2001

  • American Foundation for Pharmaceutical Education (AFPE) Fellow, 1999 – 2001

  • National Institutes of Health (NIH) Pharmacological Sciences Training Program, 1998 – 2000

  • Smithsonian Computerworld Laureate, 1999 (Article 1, Article 2, Screenshots)

  • California Boy’s State Representative, 1991

  • Eagle Scout, Boy Scouts of America, 1989

Presentations

  1. N.S. Teuscher, Population PK Studies. MDS Pharma Services Scientific Symposium, Phoenix, AZ, January 2008.

  2. M. Obaidi, PhD, D. Katzer, BS, L. Reinbolt, MS, Juki, W.K. Ng, PharmD, PhD, M. Combs, PhD, and N.S. Teuscher, PhD. Comparison of common methods used to estimate the apparent terminal elimination rate constant (Kel). AAPS Annual Meeting, 2007. (Presented by M. Obaidi.)

  3. R. Chavira, N.S. Teuscher, D. Stypinski, G. Berk. Dose proportionality and multiple-dose pharmacokinetics of ondansetron HCL oral spray (OOS) in healthy adult men and women. ASCPT Annual Meeting, 2007. (Presented by R. Chavira.)

  4. N.S. Teuscher, Advantages of performing population PK/PD throughout the drug development process. MDS Pharma Services Scientific Leadership Series, San Diego, CA, January 2007.

  5. N.S. Teuscher, H.S. Pentikis, D.S. Wells, Pharmacokinetics of ALX1-11 following intravenous infusion and subcutaneous injection in healthy post-menopausal women. AAPS Annual Meeting, 2005. (Presented by H.S Pentikis.)

  6. H.S. Pentikis, N.S. Teuscher, D.S. Wells, Population pharmacokinetic analysis of ALX1-11 in post-menopausal women. AAPS Annual Meeting, 2005. (Presented by H.S. Pentikis.)

  7. H. Wang, D.S. Wells and N.S. Teuscher, NPS 100524 and NPS 100525 – Two potent and selective inhibitors of human cytochrome P450 1A1 and 1A2, ISSX Annual Meeting, 2003. (Presented by H. Wang.)

  8. PEPT2-mediated uptake of neuropeptides in rat choroid plexus. Podium presentation at PPDM/CS Graduate Symposium, AAPS Annual Meeting, Denver, CO, October 2001.

  9. PEPT2-mediated uptake of neuropeptides in rat choroid plexus. Poster presentation at AAPS Annual Meeting, Denver, CO, October 2001.

  10. Functional evidence for the presence of PepT2 in rat choroid plexus: Studies with glycylsarcosine. Poster presentation at AAPS Annual Meeting, Indianapolis, IN, October 2000.

  11. Functional evidence for the presence of PepT2 in rat choroid plexus: Studies with glycylsarcosine. Poster presentation at Pharmaceutics Graduate Student Research Meeting, Ohio State University, June 2000.

  12. Functional evidence for the presence of PepT2 in rat choroid plexus: Studies with glycylsarcosine. Podium presentation at Graduate Student Symposium in the Pharmacological Sciences and Biorelated Chemistry, University of Michigan, March 2000.

  13. Modeling the enantioselective properties of beta-cyclodextrin to predict gas chromatography elution orders. Poster at the American Chemistry Society National Meeting, San Francisco, April 1997.

  14. Modeling the enantioselective properties of beta-cyclodextrin to predict gas chromatography elution orders. Podium at the Undergraduate Research Conference, Point Loma Nazarene College, April 1997.

Publications

  1. N.S. Teuscher, H. Shen, C. Shu, J. Xiang, R.F. Keep, D.E. Smith, Carnosine uptake in rat choroid plexus primary culture and choroid plexus whole tissue from PEPT2 null mice, J Neurochem (2004), 89:375-382.

  2. C. Shu, H. Shen, N.S. Teuscher, P.J. Lorenzi, R.F. Keep and D.E. Smith, Role of PepT2 in peptide/mimetic trafficking at the blood-CSF barrier: Studies in rat choroid plexus epithelial cells in primary culture, J Pharmacol Exp Ther. (2002), 301:820 829.

  3. N.S. Teuscher, R.F. Keep and D.E. Smith, PEPT2-mediated uptake of neuropeptides in rat choroid plexus, Pharm Res (2001), 18(6):807-813.

  4. Novotny, J. Xiang, W. Stummer, N.S. Teuscher, D.E. Smith and R.F. Keep, Mechanisms of 5-aminolevulinic acid uptake at the choroid plexus, J Neurochem (2000), 75:321-328.

  5. N.S. Teuscher, A. Novotny, R.F. Keep and D.E. Smith, Functional evidence for the presence of PEPT2 in rat choroid plexus: Studies with glycylsarcosine, J Pharmacol Exp Ther (2000), 294:494-499.

Training

  • Sheiner and Rowland’s Advanced Methods in Pharmacokinetics/Pharmacodynamics (2005, Instructors: Dennis Fisher, Leon Aarons, Mats Karlsson, Elliot Landaw, Jaap Mandema, France Mentré and Steven Shafer)

  • Binary and Categorical Data Modeling, Analysis and Simulation using NONMEM (2004, Instructors: Adrian Dunne and Bill Bachman)

  • Clinical Biomarkers in Drug Development: Efficacy Assessment, Pharmacokinetics/Pharmacodynamics and Regulatory Insights (2004)

  • ECPAG 6th Annual Conference: Validation Issues for Population PK/PD Models and Software Systems (2004)

  • Population Pharmacokinetics: Introductory NONMEM and PDx-Pop Worshop (2003, Instructors: Various instructors from Globomax, LLC)

  • PK/PD Buffalo: Pharmacokinetic/Pharmacodynamic Modeling (2003, Instructors: William J. Jusko and Daniel Weiner)

  • A Primer in Bayesian Modeling Applications Using WinBUGS and NONMEM (2003)

  • Drug-Drug Interactions and Metabolism: New Predictive Approaches to Drug Metabolism, Toxicity and Pharmacokinetics (2002)

  • 3rd International Symposium Early Toxicity Screening: Early ADME-Tox Screening Approaches (2002)